Tissue Classification Using Gene Expression Data and Artificial Neural Network Ensembles
Identifieur interne : 000F65 ( Main/Exploration ); précédent : 000F64; suivant : 000F66Tissue Classification Using Gene Expression Data and Artificial Neural Network Ensembles
Auteurs : Huijuan Lu [République populaire de Chine] ; Jinxiang Zhang [République populaire de Chine, Niger] ; Lei Zhang [République populaire de Chine]Source :
- Lecture Notes in Computer Science [ 0302-9743 ] ; 2006.
Abstract
Abstract: An important challenge in the use of large-scale gene expression data for biological classification occurs when the number of genes far exceeds the number of samples. This situation will make the classification results are unstable. Thus, a tissue classification method using artificial neural network ensembles was proposed. In this method, a feature preselection method is presented to identify significant genes highly correlated with tissue types. Then pseudo data sets for training the component neural network of ensembles were generated by bagging. The predictions of those individual networks were combined by simple averaging method. Some data experiments have shown that this classification method yields competitive results on several publicly available datasets.
Url:
DOI: 10.1007/11816102_85
Affiliations:
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<front><div type="abstract" xml:lang="en">Abstract: An important challenge in the use of large-scale gene expression data for biological classification occurs when the number of genes far exceeds the number of samples. This situation will make the classification results are unstable. Thus, a tissue classification method using artificial neural network ensembles was proposed. In this method, a feature preselection method is presented to identify significant genes highly correlated with tissue types. Then pseudo data sets for training the component neural network of ensembles were generated by bagging. The predictions of those individual networks were combined by simple averaging method. Some data experiments have shown that this classification method yields competitive results on several publicly available datasets.</div>
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